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Hutchison Whampoa
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Hutchison to develop herbal drug with Nestle

Joint venture to make medicine based on Chinese ingredients, with clinical trial soon

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Chi-Med chief executive Christian Hogg
Eric Ng

Hutchison Whampoa's pharmaceutical unit has joined forces with Swiss food giant Nestle to develop a new drug, which they said had the potential to be the first Chinese herbal-ingredient-based drug candidate to conduct a large-scale clinical trial for registration in a major disease area.

London's Alternative Investment Market-listed Hutchison China Meditech (Chi-Med), 70.4 per cent owned by Hutchison Whampoa, formed an equally owned joint venture in November last year with Nestle's wholly owned Nestle Health Science to develop nutritional and medicinal products derived from botanical plants.

Last week, the venture said the first patient had been enrolled to begin treatment in a phase-three clinical trial for a botanical-ingredient-based oral drug aimed at treating patients with moderate ulcerative colitis, a disease of the large intestine. The trial is expected to take 24 months.

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Chi-Med chief executive Christian Hogg said the firm had spent 13 years identifying 15,000 "molecular level" substances by breaking down some 1,300 herbs, and come up with a "library" of data. The substances are being screened for medical efficacy.

"Back in the early 2000s, there was a lot of talk in Asia about bringing traditional Chinese medicine to the world, but it has taken this long to do it in a scientific and methodical manner," Hogg said. "It is only now that all this effort is reaching the final stages of registration trial."

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Chi-Med started discovery work in 2003 and won approval from the United States Food and Drug Administration in 2005 to go into clinical trial for the oral drug, Hogg said last week.

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