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Cheap smartphone device detects HIV and syphilis in 15 minutes

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Users mechanically activate a negative-pressure chamber that activate the reagents, eliminating the need for an electrical pump. Photo: Tassaneewan Laksanasopin @ Columbia Engineering

US researchers have found a way to turn a common smartphone into a quick and easy device to conduct field tests for HIV and syphilis.

Using an attachment that costs US$34 to make -- a far cry from the standard $18,000 for diagnostic tests -- blood drops are tested for the diseases’ antibodies in minutes instead of hours, said the research led by Columbia University engineers.

When plugged into a smartphone’s audio jack, scientists said it mimicked the enzyme-linked immunosorbent assay (ELISA), a well-known test for HIV, and “performed almost as well.”

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The initial study, involving 96 women in Rwanda, is published in the journal Science Translational Medicine.

Scientists have developed a smartphone accessory capable of detecting multiple disease markers within 15 minutes. Photo: Samiksha Nayak @ Columbia Engineering
Scientists have developed a smartphone accessory capable of detecting multiple disease markers within 15 minutes. Photo: Samiksha Nayak @ Columbia Engineering
Experts hope that this lab-on-a-chip device could be a helpful tool, especially in places where field clinics are set up to help remote or underserved populations.
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The team, led by Samuel Sia, associate professor of biomedical engineering, is aiming for larger clinical trials first.

“Our work shows that a full laboratory-quality immunoassay can be run on a smartphone accessory,” said Sia.

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