Nine people were injured by gunshots after being caught in the crossfire as two men engaged ina gun battle on Bourbon Street, a popular tourist spot in New Orleans' celebrated French Quarter, police said.
Images captured from a surveillance camera above a bar showed people running down the famous street in the chaos of the shooting at 2.45am, the Times-Picayune reported. Police and emergency workers responded immediately and attended to victims as other revellers looked on.
New Orleans Police Chief Ronal Serpas said six victims were admitted to hospital in stable condition. The other victim's condition was not available. Some were tourists. Their names have not been released.
The victims were shot two blocks from historic Jackson Square and just around the corner from the popular Pat O'Brien's piano bar. Preservation Hall, a music venue dedicated to preserving New Orleans jazz, is also nearby.
New Orleans Mayor Mitch Landrieu pledged a swift response from law enforcement.
"Our No 1 priority is to keep New Orleans safe," Landrieu said in a statement. "These kinds of incidents will not go unanswered ... I am confident that between video evidence and eyewitness accounts, we will bring the perpetrators to justice."
Police have not determined whether the shootings might be gang-related, Serpas said.