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South Korea

Korean scientists develop biochemical breakthrough for hair loss

Newly-discovered protein disrupts signalling inside a cell linked to hair regeneration

PUBLISHED : Wednesday, 22 November, 2017, 11:26am
UPDATED : Wednesday, 22 November, 2017, 11:29am

A group of South Korean scientists has developed a new type of biochemical material to prevent hair loss, according to the country’s science ministry opening a new gateway for treatment in the field.

The team led by Choi Kang-yeol of Yonsei University discovered that a protein called CXXC5 acts as negative regulator of the Wnt signalling pathway inside of a cell that is linked to follicle development and hair regeneration in adults, the Ministry of Science and ICT said.

In order to prevent CXXC5 acting as a negative regulator of the pathway, the team successfully developed a biochemical material called PTD-DBM.

“Disrupting the CXXC5-Dishevelled interaction with a competitor peptide activated the Wnt pathway and accelerated hair regrowth and wound-induced hair follicle neogenesis,” the researchers said in a paper.

The research was funded by the science ministry, and the findings were published in the latest edition of the journal “Journal of Investigative Dermatology.”

Read the original article at The Korea Times