Manchester United feel the heat in chase for glory The FA Cup is Manchester United's most realistic chance of winning some silverware this season, and that means the pressure will be on the holders tonight when they host Middlesbrough in the fourth round. This is the tie of the round, with United currently third in the Premiership and Middlesbrough sixth. The teams have met twice already this season - a 1-1 at Old Trafford in October and United's 2-0 win at Boro on New Year's Day. That recent meeting suggests United should have the upper hand, but Boro have fielded severely under-strength sides on both occasions and should not be underestimated. Whether they can win is open to question as some key players are still missing, but they have a decent chance of a draw. Under Steve McLaren, seven of Boro's nine matches against United have had fewer than three goals and a clear-cut United win looks unlikely. Under 2.5 goals looks the best bet. There are three other all-Premiership ties - Southampton v Portsmouth, West Brom v Spurs and Chelsea v Birmingham. The south-coast derby is the most appealing match, with extra spice added by Harry Redknapp's switch from Portsmouth to their bitter rivals. Southampton have had three home wins out of three in this fixture since Portsmouth joined the Premiership last season, and their overall home form suggests they can score another tonight. West Brom have already held Spurs 1-1 at home in the league this season, and they are worth backing on the handicap. Bryan Robson's side had a confidence-boosting win over Manchester City last weekend, while Spurs' good run has petered out in recent weeks. Chelsea's biggest danger against Birmingham is complacency (remember how Scunthorpe took an early lead in their third-round tie at Stamford Bridge), and it is a match with little betting appeal. The best-value bet in the FA Cup may be Reading, who host Leicester. Reading are fourth in the Championship, with the second-best home record, and it is only seven weeks since they won 2-0 at Leicester. Derby, who are fifth in the Championship, will fancy their chances against Fulham, but the Premiership side look good value for the win. Oldham caused an upset with a 1-0 victory over Manchester City in the third round, but Bolton should end their cup dreams tomorrow night. The odds are heavily in favour of the Premiership side. There are full programmes in the major European leagues and Spain has the most eye-catching live games - Sevilla v Barcelona, Espanyol v Betis and Valencia v Bilbao. Espanyol suffered a 4-1 defeat at Deportivo last week but they rate as the best bet in the Primera Liga now that they are back at home, where only neighbours Barcelona have won this season. The standout bets in Germany are Dortmund and Leverkusen, who both look in good shape after the winter break. Dortmund resumed with a win at Wolfsburg last weekend and should be too strong at home to Borussia Monchengladbach, having already beaten them 3-2 away this season. Leverkusen were 3-0 winners at Hannover last week and their free-scoring attack is likely to overwhelm Bochum. There is a full Premiership programme in midweek with Arsenal v Manchester United the big live match. All the stats point to a close game and this could be a third Highbury draw in succession between the two sides, but Arsenal may be worth siding with on the handicap. They have lost only twice in nine home matches against United since Arsene Wenger took charge (the last defeat was in August 1999). The best midweek bets are Everton, Birmingham and West Brom. The first two are strong home teams when faced with lower-half sides and should take care of Norwich and Southampton respectively, while West Brom appeal in their big relegation clash against Crystal Palace. Best homes: Dortmund, Leverkusen, West Brom (v Crystal Palace), Birmingham, Everton (v Norwich). Best aways: Fulham, Bolton. High goals: Parma v Udinese, Osasuna v Deportivo. THOUSAND-DOLLAR WAGER Low goals: West Brom v Tottenham, Manchester United v Middlesbrough. Each week our expert tipster Nick Pulford suggests his pick of the fixtures to offer the best return-to-risk ratio for a $1,000 bet. This week: $200 win Dortmund, Leverkusen, West Brom (v Crystal Palace), Birmingham, Everton (v Norwich).