Women worldwide will feel Japanese-born Nana Komatsu's pain. A naive country girl with a talent for falling for the wrong guy, she goes looking for romance in the big city after her heart is broken by a smooth-talking married Lothario.
On the way, she meets her soul-mate: a tattooed, chain-smoking punk chick also called Nana (Osaki), who wants to be the country's biggest rock star.
Despite having little in common except a name, they bond, share a flat and fight for love and respect in the world's largest metropolis, their friendship enduring conflicts over career, family and boyfriends.
Such is the bare plot of one of Japan's biggest pop-culture sensations - a manga story with a staggering 27 million copies in print over 13 volumes, making it as much a sociological as a publishing phenomenon.
The Nana series has spawned novelettes, foreign translations, CDs, a looming US release and a movie, which will screen at the Asian Hong Kong Film festival, which opens this week.
Shibuya, Tokyo's mecca to teen fashion, is a regular haunt for youngsters sporting the Nana look - punky or demure, depending on which character they identify with.