Manchester United were upset by Blackburn twice last season and they will be anxious to avoid a repeat in tonight's crucial Premiership clash. Every game is a big one for United from now on in their bid for another treble. They have a tough Champions League double-header coming up against Roma, as well as an FA Cup semi-final against Watford, but they cannot afford to drop their guard in the league, with Chelsea poised to take advantage of any slip-up. Sir Alex Ferguson will be wary of the threat posed by Blackburn after his United side managed to win only one of the four league and cup encounters between the teams last season. The victory came at Old Trafford in the Carling Cup semi-final, but they had earlier suffered a home defeat in the league against Blackburn and later lost at Ewood Park in the league (having drawn there in the first leg of the Carling Cup semi-final). Blackburn are not going quite as well in the league this season, however, and United should gain another three points. They will need to, with Chelsea heavily favoured to win at Watford later tonight. The early live game is Liverpool v Arsenal, which does not have a great deal riding on it as both teams look booked for a top-four place to guarantee Champions League football next season, but have little chance of going any higher. Liverpool will be eager for revenge after their two home cup defeats by Arsenal earlier in the year and look a decent bet to get the win, though there is a doubt over whether Rafael Benitez will rest key players ahead of the midweek Champions League game against PSV. The best bet on another difficult Premiership programme may be Tottenham, who can extend their excellent home record under Martin Jol with victory over Reading. Tottenham have won 29 out of 38 games at home to non-Big Four teams since Jol took charge, while 13 of Reading's 15 away points have been gained against teams in the bottom seven. It is not easy to find solid bets around Europe, and the best two are Real Madrid and Werder Bremen at short odds for away wins. Real's visit to Celta Vigo gives them a good chance of extending their excellent away record against lower-ranking teams. Real have won six out of six away to teams in the bottom eight and 17th-placed Celta are on a run of just one win from their past 16 games. Werder, like Real, are very strong away to struggling sides and rate an excellent chance at 11th-placed Cottbus in the Bundesliga. Werder appear to have got over their February stumble (one point from four league games) and have recorded four wins and one draw (away to Bayern Munich) from five games in all competitions so far in March. Werder have won seven out of 11 away to bottom-half teams since their last defeat early in the 2005/06 season. Aways: Real Madrid, Werder Bremen.