Immune boost halts tumour growth
By supercharging immune cells, US researchers have been able to block the growth of cancer tumours in a small number of patients and in one case eliminate the disease. The team from Houston's Baylor College of Medicine re-engineered T-lymphocyte immune cells to boost their ability to fight neuroblastoma, a rare but deadly cancer that typically affects children. In five of the 11 patients, aged three to 10, the tumours regressed and in a sixth they were eradicated. The team now plans to use the technique to target other types of cancers, AFP reports.
Appetite-killer antibody discovered
US researchers have discovered an antibody that suppresses appetite and boosts the body's metabolic rate even during fasting. Mice given the GHR-11E11 antibody showed no signs of hunger despite going for 24 hours without food. The antibody counteracts ghrelin, a gastric hormone the body releases to encourage eating if it's not getting enough calories, Healthday.com reports. 'These findings ... strongly suggest that [GHR-11E11] might help patients reach and maintain weight-loss goals,' says team leader Kim Janda of the Scripps Research Institute in California.
Coffee raises underweight birth risk
Pregnant women who drink just one cup of coffee a day are at greater risk of having an underweight baby, warn British researchers, based on studies of more than 2,600 women. Those who drank one to two cups of coffee daily (100-199mg of caffeine) had a 20 per cent higher risk, rising to 50 per cent for those who had two to three cups. The team says caffeine from any source increases the risk of 'foetal growth restriction'. US researchers warned in January that drinking two or more cups of coffee a day doubles the risk of having a miscarriage, Reuters reports.