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Scientists seek to unravel the mystery of IQ

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Some of the world's fastest supercomputers are being set up in Hong Kong to address the age-old mystery of human intelligence.

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The study of intelligence quotient (IQ) is being conducted by BGI Hong Kong, formally known as the Beijing Genomics Institute. It will survey DNA samples from 1,000 child prodigies from China's best high schools, comparing them with samples from 1,000 children of average intelligence, searching for genetic variations.

The study will examine protein coding genes of the extremely smart children, many of whom are expected to enrol at Harvard, Yale or Cambridge. The results will be correlated with each youngster's school test scores, in hopes of learning how specific genetic variations affect intelligence.

The study, which started in 2009 in Shenzhen, is moving to a new facility in Tai Po. By the end of this month, 115 of the world's fastest sequencers - the HiSeq 2000 - will have relocated to the city. They will be able to sequence the equivalent of 1,000 human genomes a day, and soon surpass the entire sequencing output of the United States to become the world's largest sequencing centre.

The study by BGI, which receives strong financial backing from the Shenzhen and mainland governments, will be the largest-scale examination of its kind. Ethical and privacy concerns have hindered such work in America and Europe.

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In fact, ethical concerns haunt this entire subject. Ever since Nazi Germany misused science to support its murderous racist and anti-Semitic theories, Western societies have been extremely sensitive about linking genetics to IQ. Nevertheless, much scientific research suggests that IQ is strongly affected by heredity, although environment, education and nutrition also play a significant role.

According to Professor Steve Hsu, who comes to the study from the University of Oregon, scientists have identified several candidate genes that may relate to IQ, although researchers are not yet sure. He said about 50 per cent of humans' IQ is substantially inheritable. 'Scientists believe there are many genes that affect IQ, but none of them has been definitively discovered so far,' he said. 'Although there are some candidates in published work, so far the results have not been replicated.' So-called IQ genes are those that influence cognitive capabilities, including verbal and spatial abilities, perceptual speed, memory and math skills.

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