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Gene sequencing helps Hong Kong woman know herself better – but not everyone likes how this knowledge is being used

Direct-to-consumer genetic testing is a fast-growing industry, allowing anyone to have their DNA analysed, but there are concerns about accuracy, false marketing and how genetics companies use the data they collect

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Molecular scientist Harry Yeung processing DNA samples at Advanced Genomic Solutions’ laboratory in Central.
Rachel Cheungin Shanghai

If you’ve ever wondered why you often crave certain foods or have a problem losing weight, the mystery could be unravelled by taking a peek into your genetic make-up. It’s not difficult to do, with an increasing number of companies offering simple and easy genetic tests.

Being curious, I took the “health and wellness” genetic test offered by Advanced Genomic Solutions (AGS), which has offices and a lab in Central. You pay HK$4,300 (I was offered a free media trial), then simply take a swab of your mouth with a cotton bud, and a week later you get a 30-page report on the findings and a consultation.

Rather than providing raw genetic data – as is the case with many direct-to-consumer genetic testing companies – AGS prepares a short summary beside each genotype to explain the implication of your results. Some findings confirm things we already know about ourselves – in my case, an inability to metabolise alcohol and a fortunate tendency not to crave sweet things. Other findings could help me to keep in better physical shape. For example, although I have a low risk for obesity, I do have a genetic predisposition of reduced ability to utilise the B vitamin, folate.

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The AGS package comes with a free consultation, with either a nutritionist or a fitness trainer, who help clients understand their test results. I chose the nutritionist, who recommended that I consume more foods that are rich in folate, such as asparagus, kale and broccoli.

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“The test can help direct people on what exercise plans or what nutritional plans may be right for them based on their own DNA,” says Lance Bennett, a managing partner of AGS. “It’s not a one-size-fits-all plan. We can really help them tailor how they should be exercising and how they should be eating.”

In addition to the health and wellness test, AGS also offers a personalised medicine test that measures the body’s response to various medications.
Lance Bennett, a managing partner of Advanced Genomic Solutions.
Lance Bennett, a managing partner of Advanced Genomic Solutions.
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These are just a few of the growing variety of commercial genetic tests on the market – including ones on parentage, genealogy and ancestry, and predisposition to diseases – with costs ranging from several hundred to thousands of dollars. Some companies even claim they can predict children’s athletic or language abilities.

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