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Drug-resistant MRSA: Hong Kong scientists develop antibiotic that offers hope in the war against superbugs

  • Antibiotic-resistant superbugs such as MRSA are a major threat to global health, with conventional treatments failing to work
  • Experts from two Hong Kong universities have created a new drug that halts bacteria’s spread

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A Hong Kong research team, led by Dr Ma Cong (right), has developed nusbiarylins, a new class of antibiotic to help fight superbugs. Chan Shu Ting (left) is a student participating in the project.
Lily Canter

Hong Kong scientists have developed a breakthrough antibiotic to combat superbugs resistant to drugs.

The new treatment, which has been tested on human lung and skins cells, shows no sign of toxicity and will soon go forward to clinical trials on people.

Dr Ma Cong is leading the team of experts from Hong Kong Polytechnic University and Chinese University of Hong Kong’s medicine faculty. He said the research is now in the critical stages of animal studies, conducting infectious disease model studies, and pharmacokinetic studies – that determine what a body does to the drug. Only after these stages can the research move into clinical trials in people for drug development.

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“At this moment, there are very few antibiotic-related studies being able to complete such stages worldwide. Our findings so far are very promising. We believe further studies on these compounds will contribute to a new era of antibiotic discovery, contributing towards the fight against superbugs.”

Dr Ma Cong, the lead researcher, says the drug is now undergoing testing.
Dr Ma Cong, the lead researcher, says the drug is now undergoing testing.
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The World Health Organisation has declared drug resistance to be one of the biggest threats to global health in 2019, with the superbug MRSA becoming one of the most serious concerns. Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that causes infections in different parts of the body.

The search for new antibiotics has showed no progress since the mid-1980s, despite global pharmaceutical research and investment.

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