Kidney donation safe for healthy older adults Older kidney donors enjoy similar longevity and cardiovascular health as other healthy mature individuals, according to a new study published in the American Journal of Transplantation . The findings may provide reassurance to older people considering donation. Over the past two decades, live kidney donation by individuals aged 55 years and older has become more common. In the first study to look closely at the safety of donating for older kidney donors, Peter Reese, assistant professor of medicine in renal-electrolyte and hypertension division, at the Perelman School of Medicine at the University of Pennsylvania, matched 3,368 older donors 1:1 to older healthy non-donors and followed them for a median of 7.8 years. He found that mortality rates were not different between donors and matched pairs. Donors also did not have an elevated risk of diabetes, a risk factor for cardiovascular and kidney diseases, compared with matched non-donors. Molecules in urine may be signal for premature birth Testing for the presence of specific molecules in the urine of women during early stages of pregnancy could give an indication of whether the baby will be born prematurely or the fetus will suffer poor growth, according to research published in BMC Medicine . Identifying these conditions early in pregnancy could potentially help reduce complications, although more work is needed before the findings can be translated to clinical settings. Researchers from Imperial College London and the University of Crete analysed the metabolites - small molecules excreted in urine - of 438 pregnant women. They found that an elevated urinary level of the amino acid lysine was associated with spontaneous premature birth. In contrast, increased levels of N-acetylated glycoprotein were found in women who had to be induced early. Decreased levels of a third group of molecules: acetate, formate, tyrosine and trimethylamine were linked to poor fetal development. Women with decreased levels of these metabolites also showed signs of an increased risk of diabetes. Vaccine no clot threat, say researchers A vaccine that protects against four strains of the human papillomavirus, which can lead to cervical cancer, does not increase the risk of blood clots in women, researchers say in the Journal of the American Medical Association . Based on 500,000 women aged 10 to 44 who received the HPV vaccine between 2006 and 2013, the researchers in Denmark found no evidence of an increased risk of venous thromboembolism (VTE) in the 42 days after the shot, which they define as the main risk period. Of the 500,000, there were 4,375 cases of blood clots, and of those, 889 had been vaccinated during the study period. When researchers adjusted for use of oral contraceptives, which can increase the risk of blood clots, they found no association between VTE and the vaccine. Tuberculosis threat greater than first reported Twenty-five per cent more children are falling ill with tuberculosis than the United Nations had thought, with more than 650,000 hit by the disease each year in the 22 worst affected countries, say specialists. Reporting in The Lancet , they say that about 53 million children under 15 are living with latent tuberculosis infection, a condition that can turn active any time. A contagious disease of the lungs, tuberculosis is caused by a microbe called Mycobacterium tuberculosis. Millions of people are latent cases, meaning they are infected with the germ but have yet to develop any symptoms. Last year, the WHO estimated there were 530,000 cases of active cases among children younger than 15 years in 2012. But this estimate was based on reporting by paediatric doctors - a technique faulted by many experts because methods and reliability vary greatly from country to country.