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Japan
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Japan sees world’s first death from tick-borne Oz virus

  • A woman in her 70s died of myocarditis last year after she was diagnosed with an infection caused by Oz virus
  • No vaccine exists against the virus, which was first detected in 2018 in the Amblyomma testudinarium tick found in Japan’s Ehime prefecture

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An electron micrograph of the Oz virus. Photo: EPA-EFE/National Institute of Infectious Diseases
Kyodo

A woman in her 70s died in Ibaraki prefecture, northeast of Tokyo, after contracting the Oz virus, making her case the world’s first death by the possibly tick-borne infection, Japanese authorities said on Friday.

The virus was discovered in the country in 2018, and while there may have been cases of humans and wild animals being infected, there had been no confirmation of its onset on a person until now, the authorities said.

The woman went to a medical institution in the summer of 2022 after developing symptoms, including fever and fatigue, according to the prefectural government and the health ministry.

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She was diagnosed with pneumonia, but after her condition worsened, she was hospitalised, and an engorged tick was found on her upper right thigh, they said.

She died of myocarditis, an inflammation of the heart muscle, 26 days after she was hospitalised.

No vaccine exists against the Oz virus, which has not been found outside Japan, according to the National Institute of Infectious Diseases in Tokyo.
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