On the genetic and drug trail to contain the deadly coronavirus in China
- HIV medications and genome sequencing are two technologies being used in response to the outbreak as scientists search for a vaccine and treatment
- Researchers say the new pathogen is closer to a bat coronavirus than Sars
Xu Wenbo, director of the virus institute at Chinese Centre for Disease Control and Prevention (CDC) said researchers had isolated virus strains for vaccine development, state-run news portal Chinanews.com reported on Sunday.
Xu said researchers had used “high-throughput genetic sequencing” technology to identify the pathogen’s genome one day after the first four samples of the coronavirus were sent from Wuhan on January 2.
But the CDC did not give a timeline for plans to develop a vaccine.
The Wuhan pathogen is from a large family of viruses called coronaviruses, one of which also caused the deadly 2002-03 outbreak of severe acute respiratory syndrome (Sars).
But researchers in Beijing said the Wuhan coronavirus could be a novel virus rather than an evolved version of Sars.
Tan Wenjie, also from the CDC virus institute, said scientists compared the genome sequence with those of a dozen other viruses, and determined that 2019-nCoV was 82 per cent similar to Sars but also 90 per cent similar to a bat coronavirus sample from Zhoushan in eastern China’s Zhejiang province, state broadcaster China Global Television Network reported.
Tan said the Wuhan virus was “a distant relative” of Sars, adding that it was still too early to say whether the new virus came from bats.
With the death toll and number of cases rising quickly on the weekend, China is struggling to treat people diagnosed with the illness.
Peer-reviewed medical journal The Lancet reported on Friday that a clinical trial using the two drugs to treat the patients with the coronavirus was under way.
The Ministry of Science and Technology is coordinating the efforts of 11 government and military departments to streamline scientific research on containing the spread of the illness.
But it remains an open question if any effective and safe vaccine can be developed soon enough in this case, given that researchers around the world are still looking for one for Sars and Middle East respiratory syndrome, or Mers, another viral respiratory disease caused by a novel coronavirus transmitted to humans by camel.
About 17 years after the Sars outbreak, the then State Food and Drug Administration said in November that human trials for an experimental Sars vaccine were expected to begin after success with trials on monkeys.