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Coronavirus pandemic
ChinaScience

Tuberculosis vaccine may play role in reducing Covid-19 death rate, study says

  • US researchers compared data across the globe, finding places where people were inoculated against TB had lower mortality rates
  • Findings are preliminary, and it is not clear why, but they suggest BCG could ‘train’ a child’s innate immune response

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US researchers made the TB vaccine link after comparing data on Covid-19 mortality rates, but caution that the results are preliminary. Photo: Shutterstock
Stephen Chen
A century-old tuberculosis vaccine could be playing a role in reducing the death rate from Covid-19 in countries where it is widely used, according to a preliminary US study.

Researchers from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health made the link to Bacille Calmette-Guerin, or BCG, after comparing data on Covid-19 mortality rates across the globe.

They found that some Latin American regions – including Pernambuco, Rio de Janeiro and Sao Paulo in Brazil and Mexico City in Mexico – had considerably lower death rates than states in the US such as New York, Illinois, Louisiana and Florida.

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“This is remarkable, considering that [these parts of] Latin America have much higher population densities than the North American states analysed, including New York,” co-author Carolina Barillas-Mury wrote in a peer-reviewed paper in the Proceedings of the National Academy of Sciences of the United States of America on Tuesday.

A customer gets his temperature checked at a restaurant in Sao Paulo, Brazil on Monday. The city was found to have a lower Covid-19 death rate than some parts of the US. Photo: Bloomberg
A customer gets his temperature checked at a restaurant in Sao Paulo, Brazil on Monday. The city was found to have a lower Covid-19 death rate than some parts of the US. Photo: Bloomberg
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In Europe, Germany also had surprising results – the death rate from Covid-19 was 2.9 times higher among people from the former West Germany than those in the former East Germany. And the mortality rate was four times higher in Italy than in Finland.

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