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Coronavirus pandemic
ChinaScience

Coronavirus: could cells that fight common cold help people beat Covid-19?

  • German researchers say findings could have significant implications regarding herd immunity thresholds and projections for the Covid-19 pandemic
  • US team says its study provides strong direct molecular evidence that memory T-cells can see similar sequences between common cold coronaviruses and SARS-CoV-2

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Studies suggest previous exposure to common cold coronaviruses could help people fight Covid-19. Photo: EPA-EFE
Simone McCarthy
Long before the coronavirus that causes Covid-19 was detected, four other coronaviruses had been circulating among people, causing about one in five common colds.

While much is unknown about the novel coronavirus, evidence is emerging that these cold-causing viruses might leave behind “memories” in our immune system that could affect how the body fights Covid-19.

New research published by separate teams in the US and Germany suggests certain immune cells involved in the defence against the common cold also react when exposed to SARS-CoV-2, as the novel coronavirus is known.

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While neither study showed whether this pre-existing immune cell memory affects Covid-19 clinical outcomes, both teams said evidence of a “cross-reactive” immune response could explain why some people have much more severe responses to Covid-19 than others, but more research was needed.

Studies suggest certain immune cells involved in the defence against the common cold also react when exposed to SARS-CoV-2 (pictured). Photo: EPA-EFE
Studies suggest certain immune cells involved in the defence against the common cold also react when exposed to SARS-CoV-2 (pictured). Photo: EPA-EFE
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The research comes as scientists around the world try to understand how the human immune system fights Covid-19 to help them design vaccines and drugs to fight it.

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