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Chinese coronavirus vaccines
ChinaScience

China’s single-shot Covid-19 vaccine safe for children at lower dosage, tests find

  • Trial involving 150 children found those given a lower dose of CanSino vaccine had a stronger antibody response than adults given a booster shot after 56 days
  • The antibody readings, however, did not show to what extent the vaccine could offer protection against Covid-19, researchers cautioned

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Researchers lowered the dosage after a few children developed fever and headaches. Photo: AFP
Reuters
CanSino Biologics’ single-dose Covid-19 vaccine, given at a lower dosage than that for adults, is safe and triggers an immune response in children aged six-17, results from a small trial showed.

Researchers decided to lower the dosage after a few participants developed fever and headaches graded at level 2 severity – the second-lowest of four levels.

In children, the lower dose triggered higher antibody levels than the dosage approved for use in adults in China, according to the peer-reviewed finding.

01:45

China administers nearly 2 billion Covid-19 vaccine doses as Delta variant appears under control

China administers nearly 2 billion Covid-19 vaccine doses as Delta variant appears under control

The trial recruited 150 children and around 300 adults.

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The results also showed that children given one lower dose had a stronger antibody response than adults who were given a booster shot 56 days after the first dose.

But the antibody readings did not show to what extent the vaccine could offer protection against Covid-19, researchers from a Chinese disease control agency, CanSino and other Chinese institutes cautioned in a paper.

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