-
Advertisement
Chinese coronavirus vaccines
ChinaScience

Chinese mRNA booster fights Omicron 4 times better than inactivated Covid-19 vaccines, researchers say

  • AWcorna vaccine produced 4.4 times more Omicron antibodies than Sinovac booster, scientists behind clinical trial write in Cell Research journal
  • Home-grown mRNA jab could be China’s best bet against the highly transmissible variant, with Pfizer-BioNTech’s version yet to clear regulatory hurdle

Reading Time:2 minutes
Why you can trust SCMP
67
AWcorna, China’s first mRNA vaccine, has been developed by  Abogen Biosciences, Walvax Biotechnology, and the Academy of Military Medical Sciences. Photo:  AP
Zhuang Pinghui
China’s home-grown mRNA Covid-19 vaccine produces stronger antibodies against the Omicron variant than inactivated shots when given as a booster, a study has shown.

The AWcorna vaccine is the latest in a string of Chinese shots seeking to improve public immunity against the highly transmissible strain of the Sars-Cov-2 coronavirus that causes Covid-19, in a country where most residents were inoculated with inactivated doses.

Nearly 90 per cent of China’s population have been fully vaccinated and about 59 per cent have received a booster. But only about 4.8 per cent of the boosted population received a vaccine using a different technology.

06:41

Third Chinese Covid-19 vaccine gets emergency-use approval from WHO

Third Chinese Covid-19 vaccine gets emergency-use approval from WHO

“The effectiveness of AWcorna in preventing infection by Sars-CoV-2 and other variants of concern remains to be determined,” researchers behind the study wrote in peer-reviewed journal Cell Research earlier this week.

Advertisement

“[However] the induction of potent neutralising antibodies against wild type [original strain coronavirus] and variants of concern, as well as the affordable safety profile, support the emergency use of AWcorna as a heterologous booster in China.”

The AWcorna vaccine, formerly known as ARCoV and co-developed by Walvax Biotechnology, Suzhou Abogen Biosciences Co and the Academy of Military Medical Sciences, appears to be China’s best chance at getting a home-grown mRNA vaccine in a market dominated by inactivated vaccines.
Advertisement
It has been in the final stage of clinical trials for months, while the globally distributed Pfizer-BioNTech mRNA vaccine remains stuck in the approval process for import by Chinese partner Shanghai Fosun Pharmaceutical Co (Fosun Pharma).
Advertisement
Select Voice
Choose your listening speed
Get through articles 2x faster
1.25x
250 WPM
Slow
Average
Fast
1.25x