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Echo Xie

He Jiankui, the Chinese scientist who sparked controversy when he created the world’s first gene-edited babies, said he has relocated to Beijing and is applying for government funding for a DNA synthesiser project.
“I have come to Beijing for development,” He posted last month on Weibo, China’s Twitter-like microblogging platform.
In a separate post, He said he wanted to research a new DNA synthesiser project and was preparing to apply to the government for funding.
“[I will] continue the scientific research and serve the country,” He wrote on Weibo.


When contacted by the South China Morning Post on Wednesday, He declined to elaborate on his plans, saying it was not convenient for him to talk.
The project aims to raise 50 million yuan (US$7.2 million) to develop China’s first third-generation DNA synthesis platform in three years, according to the research proposal He posted on Weibo.
“DNA sequencing is like ‘reading’ data from a computer disk, while DNA synthesis is like ‘writing’ data from the disk,” He wrote.
“The biggest use of the DNA synthesiser I plan to make is for information storage. A fingernail-sized piece of synthetic DNA can store the contents of books from the entire national library.”
He added that the DNA synthesiser combined key technologies including DNA synthesis, chip and other electronic component manufacturing, as well as high-end mechanical engineering.
Chinese scientists develop new ‘reversible’ gene-editing technique
“We … [should] seize the new technological and economic growth opportunities from the synthetic biology sector,” He wrote in the research proposal.
He stunned the world in 2018 when he announced that he had created two genetically modified twin girls, “Lulu” and “Nana”. A third child, “Amy”, was born the following year. The welfare and whereabouts of the three girls have not been made public.
He used the gene-editing tool CRISPR-Cas9 to rewrite the CCR5 gene of three embryos for the purpose of making them resistant to HIV.
Scientists say genome-editing technologies have the potential to cure a range of genetic diseases in the future but that the technologies are immature. Until now, the use of these tools in embryos has been limited to research.
Bioethicists look at how to care for China’s gene-edited babies
He was freed from jail earlier this year. He was detained and sentenced to three years in jail and fined 3 million yuan (US$432,000) for conducting “illegal medical practices” in 2019.
Before that, He was fired from the Southern University of Science and Technology in Shenzhen, where he had been an associate professor.
Earlier this year, two prominent Chinese bioethicists called on the Chinese government to better protect the three gene-edited girls.
In a proposal submitted to the National Health Commission in February, the bioethicists suggested a dedicated “research and care organisation” be set up and funds allocated to look after the children.


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Science

He Jiankui, creator of world’s first gene-edited babies, seeks Chinese government funding for DNA synthesiser

Chinese scientist He Jiankui speaking in Hong Kong at a human genome conference in November 2018, the same month he revealed his work on gene-edited babies. Photo: Sam Tsang

Chinese scientists develop new ‘controllable and reversible’ gene-editing technique

The new technique targets the RNA and not the DNA. Photo: Shutterstock


Chinese scientists say ‘Midas’ touch helps to fine-tune CRISPR gene editing

Chinese researchers say they have designed techniques that could minimise “off-target effects” of gene editing. Photo: Shutterstock

He Jiankui addresses a gene editing conference in Hong Kong in November 2018. Photo: AP

Nobel Prize for Chemistry awarded to US-French duo for gene-editing research that could pave the way to curing inherited diseases

US biochemist Jennifer Doudna, left, and French microbiologist Emmanuelle Charpentier. Photo: AP

A screen shows French researcher in Microbiology, Genetics and Biochemistry Emmanuelle Charpentier (L) and US professor of Chemistry and of Molecular and Cell Biology, Jennifer Doudna during the announcement of the 2020 Nobel laureates in Chemistry during a press conference at the Royal Swedish Academy of Sciences, in Stockholm, on October 7, 2020. (Photo by Henrik MONTGOMERY / various sources / AFP) / Sweden OUT

News

China


Controversial scientist freed this year from jail for illegal medical practices has relocated to Beijing for US$7.2 million project
‘Biggest use of the DNA synthesiser I plan to make is for information storage’, says former Shenzhen-based professor



The controversial scientist freed this year from jail for illegal medical practices has relocated to Beijing for his proposed US$7.2 million project.


Technology

China technology