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Study using mosquitoes to deliver vaccines has Chinese researchers buzzing

  • Researchers harness mosquitoes to deliver re-engineered vaccines for animals
  • Study may pave the way to reduce viral infections like Zika and could help save endangered wildlife

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A team of Chinese researchers has harnessed mosquitoes to deliver re-engineered vaccines that could help save animal populations. Photo: Shutterstock Images
Zhang Tongin Beijing

A team of Chinese scientists has provided new evidence that one of humankind’s most annoying, or even deadly, pests could be a key ally in the fight against viral diseases.

In an article published in the peer-reviewed journal Nature Communications on December 16, researchers said they had developed new technology that can turn a mosquito into a flying vaccine carrier to immunise animals in the wild.

“Our study provides a future avenue for developing a mosquito-delivered vaccine to eliminate zoonotic viruses,” said Professor Zheng Aihau, with the Institute of Zoology’s State Key Laboratory of Integrated Management of Pest Insects and Rodents at the Chinese Academy of Sciences, who led the research.

01:46

Japanese mosquito repellent may curb dengue fever uptick in Southeast Asia

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The finding could not only lead to a reduced spread of viruses within populations of hard-to-access wildlife hosts, but also protect endangered species from viral diseases, the researchers said in the paper.

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The researchers found that bites in wildlife from genetically modified mosquitoes triggered a strong, long-lasting immune response. Once immunised, the animals resisted infections, thus helping to prevent the early spread of many viruses, including the once widespread Zika virus (ZIKV).

Zika belongs to the flavivirus genus and is transmitted primarily by Aedes mosquitoes. People infected by the virus can have symptoms ranging from rashes and fever to muscle and joint pain.

But Zika virus infections during pregnancy can cause infants to be born with microcephaly (an abnormally small head or cranial capacity) and other congenital malformations. The infection can also lead to premature birth or miscarriage.

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