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Chinese-Dutch team discovers how single cell can regenerate into brand new plant: study

‘Remarkable’ secret involves flipping two genetic switches, could safeguard world food security and transform human regenerative therapy

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A plant cell as seen under a microscope. The insights gained into cellular reprogramming by the Chinese-Dutch team could eventually lead to breakthroughs in regenerative medicine, such as organ repair or tissue regeneration in humans. Photo: Shutterstock
Holly Chik

Scientists in China and the Netherlands say they have discovered how a single plant cell can regenerate into an entirely new plant by flipping two genetic switches.

They said the findings could help scientists develop technologies to quickly regenerate high-yield resilient crops to safeguard global food security and offer cross-species insights into regenerative medicine in humans.

Researchers at Shandong Agricultural University and BGI-Research in China collaborated with peers at Radboud University in the Netherlands and published their findings in the peer-reviewed journal Cell last month.

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The formation of an embryo from a single cell is one of the most profound processes in biology, they wrote.

In both plants and animals, embryos typically arise from a fertilised egg, a cell that has the capacity to generate all cell types required to form a complete organism, according to the paper.
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This ability was thought to belong only to fertilised eggs. But in plants, differentiated somatic cells – referring to all the cells other than sperm and egg cells – can regain this ability and initiate embryogenesis under appropriate conditions. This phenomenon is known as somatic or non-reproductive embryogenesis.

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