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Rare coronavirus patient’s mild symptoms but long illness may point to ‘chronic’ mutation: researchers

  • Potential ‘chronic patients’ may have prolonged ability to infect their surroundings, Chinese researchers warn
  • ‘The virus and the host may even form a symbiotic relationship,’ they say

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Chinese researchers warn there may be chronically infected patients who could spread the infection in their surroundings. Photo: Xinhua
Chinese researchers have raised the possibility that a new subtype pathogen of Covid-19 that has low toxicity but with prolonged ability to infect others might have occurred after observing a rare case in which the disease appeared to be “chronic”, pointing to the possibility of a mutation.

The researchers warn there may be more “chronic infected patients” who carry the infection into their surroundings and trigger an outbreak.

A middle-aged man whose symptoms were not severe appears to have formed a “dynamic balance” with the coronavirus after an extremely prolonged illness lasting 49 days, Chinese military researchers reported in a preprint article on Medrxiv.org last week.

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The patient had been observed to have both a high Covid-19 viral load and, at the same time, his immune cell indicators had remained stable.

“The virus and the host may even form a symbiotic relationship,” said the researchers from the Army Medical University in Chongqing, No 967 Hospital of PLA, Dalian, and General Hospital of the PLA Central Theatre Command in Wuhan.

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A middle-aged man was observed to have Covid-19 for 49 days, a prolonged period compared to other patients. Photo: EPA-EFE
A middle-aged man was observed to have Covid-19 for 49 days, a prolonged period compared to other patients. Photo: EPA-EFE

As the signs showed that his body could not eliminate the coronavirus with regular therapy and that he might still have been infectious, the patient was treated with a plasma transfusion from recovered Covid-19 patients.

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