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Coronavirus pandemic
Hong KongHealth & Environment

Exclusive | Coronavirus: Hong Kong study finds ‘substantial’ antibody-level difference between BioNTech, Sinovac jab recipients

  • Amount of antibodies does not directly reflect individual’s level of protection, but researcher notes increasing evidence that higher levels generally correspond with greater immunity against infection
  • Objective of study was to estimate incidence of natural infections over time and level of population immunity due to infections and vaccinations

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People leave after being given the BioNTech vaccine at Lai Chi Kok Park Sports Centre. Photo: Jonathan Wong
Victor Ting
A major Hong Kong study has found “substantially higher” levels of antibodies in people vaccinated against Covid-19 with the German-made BioNTech vaccine, compared with those who received China’s Sinovac shots.
The presence of antibodies is a sign that the vaccine is working to protect an individual, although the quantity of the proteins generated by the body’s immune system to identify and neutralise the coronavirus does not directly correlate to the level of immunity.

While the study’s findings do not place the merits of taking one vaccine above the other, they have raised questions about a government plan to shorten the quarantine period for vaccinated travellers arriving in Hong Kong based on antibody tests.

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Lead researcher Professor Benjamin Cowling, an epidemiologist at the University of Hong Kong (HKU), told the Post the results also suggested that some of those who had received the Sinovac vaccine might need a booster shot.

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The government-commissioned study was conducted by HKU’s school of public health and involved tracking the antibody responses of 1,000 people who received either vaccine. Supported by the Health and Medical Research Fund, the objective of the study was to estimate the incidence of natural infections over time and the level of population immunity due to infections and vaccinations.

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