Genes inherited from Neanderthals continue to influence clinical conditions in modern humans, including depression and addiction
Other effects were seen in the blood – some Neanderthal variants led to increased blood coagulation, which would be helpful in healing more quickly from wounds and preventing pathogens from entering the body.
If you can’t seem to quit smoking, or have a tendency to become depressed, you might be able to blame your Neanderthal heritage.
After a massive study linking tens of thousands of modern people’s medical records to their genetic histories, certain genes inherited from Neanderthals have been linked to psychiatric disorders, blood clotting and addictive behaviours, researchers said on Friday.
The legacy of human ancestors from Africa interbreeding with Neanderthals in Europe has left today’s people – at least those who come from Europe or Asia – with anywhere from one to four per cent of their genes traceable to Neanderthals, scientists announced in 2010.
This study, in the February 12 edition of the journal Science, is the first to compare Neanderthal DNA in the genomes of a large population of adults of European ancestry – some 28,000 people – and their health records to show a “subtle but significant impact on modern human biology,” said the article by John Capra, an evolutionary geneticist and assistant professor of biological sciences at Vanderbilt University.
“Our main finding is that Neanderthal DNA does influence clinical traits in modern humans,” he said. “We discovered associations between Neanderthal DNA and a wide range of traits, including immunological, dermatological, neurological, psychiatric and reproductive diseases.”
We discovered associations between Neanderthal DNA and a wide range of traits, including immunological, dermatological, neurological, psychiatric and reproductive diseases
The study found that modern human DNA contains 135,000 gene variants that come from Neanderthals, who disappeared around 30,000 years ago. They also found that these variants were linked to a higher risk of 12 illnesses, including depression and heart attack.