Update | US Senator John McCain, former presidential candidate, is diagnosed with brain cancer

Veteran US Senator John McCain, a former prisoner of war and the 2008 Republican presidential nominee, has been diagnosed with brain cancer, his office announced Wednesday.

The 80-year-old lawmaker from Arizona underwent surgery to remove a blood clot from above his left eye last week and tests “revealed that a primary brain tumour known as a glioblastoma was associated with the blood clot,” the Mayo Clinic, whose doctors performed the surgery in Phoenix, said in a statement released by McCain’s office.

“The senator and his family are reviewing further treatment options,” the statement added, noting they may include a combination of chemotherapy and radiation.

Glioblastoma is a particularly aggressive cancerous brain tumour affecting adults. It is of the same category of cancer that led to the death of another icon of the US Senate, Ted Kennedy, who died in 2009 at age 77.

It is not McCain’s first bout with cancer. Doctors removed several malignant melanomas on McCain’s skin in the 1990s and 2000s, including an invasive melanoma in 2000.

Experts had said this week that McCain’s latest operation suggested the possibility of a return of cancer.

McCain’s office said the senator “is in good spirits as he continues to recover at home with his family in Arizona,” and that he will consult with his care team about when he might be able to return to work in Washington.