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Medicine
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The interstitium is a newly discovered part of the human anatomy and it may explain how cancer spreads

Nobody was looking for the interstitium because no one knew it was there

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Neil Theise, co-author of the study of the interstitium. Photo: Reuters
Agence France-Presse

Thanks to a laser-equipped mini-microscope developed by a French start-up, scientists have discovered a previously undetected feature of the human anatomy that could help explain why some cancers spread so quickly.

Nobody was looking for the interstitium, as the new quasi-organ is called, because no one knew it was there, at least not in complex form revealed in a study published this week.

As with many breakthroughs in medicine and science, it was – to paraphrase Louis Pasteur’s oft-quoted dictum – a case of chance favouring the prepared.

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In 2015, a pair of doctors at New York’s Beth Israel Medical Centre, David Carr-Locke and Petros Benias, found something unexpected while using the hi-tech endoscopic probe to look for signs of cancer on a patient’s bile duct.

There on a screen, clear as day, was a lattice-like layer of liquid-filled cavities that did not match anything found in the anatomy chapters of medical school textbooks.

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“These have no obvious correlate to known structures,” they noted drily in the journal Scientific Reports.

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