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Friends star Matthew Perry’s tragic last words revealed: ‘Shoot me up with a big one’

  • In his final hours, the actor told live-in assistant Kenneth Iwamasa – one of 5 people charged in his death – to inject him with ketamine

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Matthew Perry attends the GQ Men of the Year Party 2022 at The West Hollywood EDITION on Nov. 17, 2022, in West Hollywood. (Phillip Faraone/Getty Images/TNS)
Tribune News Service

Matthew Perry’s last words were instructions to his live-in assistant – one of five people charged in the actor’s ketamine-related death last year – to administer the drug to which he’d become addicted.

The 54-year-old Friends star, who was found dead in his hot tub last October from “the acute effects of ketamine”, reportedly told Kenneth Iwamasa to “shoot me up with a big one” during his final hours, according to court documents obtained by NBC News this week.

Iwamasa, 59, has pleaded guilty to one count of conspiracy to distribute ketamine causing death. According to authorities, he admitted to repeatedly injecting the actor with ketamine in the weeks leading up to his death, despite having no medical training, and did so multiple times on the day Perry died.

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On October 28, Iwamasa allegedly injected Perry with the dissociative anaesthetic three different times – at 8.30am, again at 12.45pm, and “approximately 40 minutes later”, according to the details laid out in Iwamasa’s plea agreement.

“Victim M.P. [Matthew Perry] asked defendant to prepare the jacuzzi for Victim M.P. and told defendant, ‘shoot me up with a big one’, referring to another shot of ketamine,” the document reads.

An image from the indictment against several people charged in Matthew Perry’s death shows alleged evidence discovered in the case. Photo: US District Court Central District of California via AFP
An image from the indictment against several people charged in Matthew Perry’s death shows alleged evidence discovered in the case. Photo: US District Court Central District of California via AFP

After doing so, Iwamasa left the house to run errands only to find the actor face down in the hot tub upon his return.

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