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Coronavirus pandemic
This Week in AsiaHealth & Environment

Coronavirus vaccine: in Singapore, 432 report side effects but experts ‘reassured’

  • More than 113,000 people were given first dose of the Pfizer-BioNTech vaccine, after which 432 people suffered side effects, including three who had anaphylaxis
  • Despite number of adverse reactions, experts say recipients were watching for unusual effects; fewer will be reported as vaccinations increase

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Singaporeans aged 70 years and above wait to get a dose of the Covid-19 vaccine on January 27. Photo: Reuters
Kok Xinghuiin Singapore
Health experts in Singapore say the relatively high rate of adverse effects from the initial Covid-19 vaccinations delivered by the island nation is not alarming, and is in fact reassuring.
Singapore has given more than 113,000 people the first dose of the Pfizer-BioNTech vaccine, after which 432 suffered common side effects, including three people who had anaphylaxis, which is a rapid onset of severe allergic reactions. The data was released by the Ministry of Health on Thursday night as the country embarked on inoculating the general population, with those aged 70 and above getting their first shot on Wednesday. Prime Minister Lee Hsien Loong is one of the 50 who has received their second shot of the vaccine.

The ministry said the three cases of anaphylaxis were “quickly resolved” by health care professionals, and had happened to individuals in their 20s and 30s who had a history of allergies, including allergic rhinitis and food allergies such as to shellfish. None had a history of anaphylaxis, which would have precluded them from the vaccine, and all have been discharged from hospital after a day’s observation or treatment.

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This puts Singapore’s incidence rate of anaphylaxis at about 2.7 per 100,000 doses administered, compared with other jurisdictions’ one to two per 100,000 doses administered. The ministry said initial variations in the incidence rate were expected given the numbers vaccinated in the island nation were relatively small.

Dr Jeremy Lim, an associate professor at the National University of Singapore’s Saw Swee Hock School of Public Health, lauded the country for being transparent with the data of adverse effects to the vaccine.

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He said the three anaphylaxis cases highlighted that the reaction could actually be effectively managed without long-term complications when strong medical facilities were within easy access, and added that incidence rates in Singapore were likely to look similar to other jurisdictions when vaccinations were scaled up.

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