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Coronavirus pandemic
This Week in Asia

Explainer | Which drugs are most effective to treat Covid-19 patients?

  • Vaccination remains a key priority for many countries but infectious disease experts say effective Covid-19 treatments will still be necessary
  • Several large-scale clinical trials are still under way around the globe to assess and determine the most promising medications

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The main factor in poor outcomes globally has been overwhelmed hospitals without enough beds, ventilators and oxygen. Photo: AFP
TODAY

As nations around the world race to vaccinate citizens against Covid-19, medical experts are still working to identify the best treatments for those who become ill.

Several large-scale clinical trials are still under way around the globe to assess and determine the most promising drugs that can be used to treat Covid-19 even when most people are fully vaccinated.

Why treatments are needed

Vaccination remains a key priority for many countries in managing and reopening after the pandemic, but infectious disease experts believe effective Covid-19 treatments will still be necessary for patients who become infected. These will include those who are not eligible or do not want to get vaccinated against Covid-19.
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“Treatment of Covid is critical because the vaccine is not 100 per cent,” said Professor Dale Fisher, an infectious disease expert from the National University of Singapore (NUS) Yong Loo Lin School of Medicine. “Some will always refuse vaccination and, on occasion, a vaccinated person could get sick. That’s expected so we want the best options found and available.”

Trials of Covid-19 drugs

The largest of the trials, involving more than 12,000 patients, is being conducted at Oxford University. Since March 2020, the Recovery trial has studied several drugs for their efficacy in treating Covid-19 patients.

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Some drugs have been shown to be ineffective, such as the anti-malaria drug hydroxychloroquine, which was promoted as a potential treatment by former US president Donald Trump.
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